Basic Information
ID: ALA3817137
Type: Binding
Description: Inhibition of EGFR T790M/L858R double mutant autophosphorylation in human NCI-H1975 cells incubated for 2 hrs by ELISA
Organism: Homo sapiens
Cell type: NCI-H1975
Activity Charts
Bioactivity
Activity Types for Assay ALA3817137
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 471.57 | 2.51 | 2.51 |
| 485.60 | 2.90 | 2.90 |
| 519.61 | 4.32 | 4.32 |
| 507.60 | 4.15 | 4.15 |
| 537.60 | 4.46 | 4.46 |
| 537.60 | 4.46 | 4.46 |
| 549.64 | 4.33 | 4.33 |
| 533.64 | 4.34 | 4.34 |
| 533.64 | 4.71 | 4.71 |
| 519.61 | 4.32 | 4.32 |
| 533.64 | 4.38 | 4.38 |
| 533.64 | 4.38 | 4.38 |
| 533.64 | 4.38 | 4.38 |
| 520.60 | 3.71 | 3.71 |
| 520.60 | 3.71 | 3.71 |
| 436.48 | 3.59 | 3.59 |
| 466.51 | 3.05 | 3.05 |
| 535.61 | 3.38 | 3.38 |
| 548.66 | 3.30 | 3.30 |
| 533.64 | 4.71 | 4.71 |
| 547.67 | 5.10 | 5.10 |
| 547.62 | 4.24 | 4.24 |
| 563.62 | 3.21 | 3.21 |
| 590.69 | 3.78 | 3.78 |