Basic Information
ID: ALA3820761
Type: ADME
Description: Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 4 mins by LC-MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA3820761
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 531.44 | 4.21 | 4.21 |
| 369.24 | 3.40 | 3.40 |
| 423.21 | 3.94 | 3.94 |
| 405.27 | 3.93 | 3.93 |
| 459.24 | 4.47 | 4.47 |
| 290.34 | 2.64 | 2.64 |
| 344.31 | 3.18 | 3.18 |
| 320.37 | 2.65 | 2.65 |
| 326.38 | 3.17 | 3.17 |
| 356.40 | 3.18 | 3.18 |
| 410.37 | 3.72 | 3.72 |