Basic Information
ID: ALA3820951
Type: Binding
Description: Inhibition of PAK1/2 in human EBC1 cells assessed as phosphorylation of MEK1 at serine 298 after 2 hrs by HTRF assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: EBC1
Target: Serine/threonine-protein kinase PAK 1/PAK 2(ALA3885636)
Document: ALA3817726
Inhibition of PAK1/2 in human EBC1 cells assessed as phosphorylation of MEK1 at serine 298 after 2 hrs by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3820951
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 518.07 | 5.04 | 5.04 |
| 492.97 | 3.22 | 3.22 |
| 450.93 | 2.96 | 2.96 |
| 421.89 | 3.63 | 3.63 |
| 463.93 | 3.40 | 3.40 |
| 437.89 | 2.61 | 2.61 |
| 451.91 | 3.26 | 3.26 |
| 493.95 | 3.03 | 3.03 |
| 486.91 | 3.21 | 3.21 |
| 526.98 | 3.86 | 3.86 |
| 506.99 | 2.94 | 2.94 |
| 508.99 | 3.66 | 3.66 |
| 506.99 | 2.86 | 2.86 |
| 570.00 | 3.02 | 3.02 |
| 452.90 | 2.65 | 2.65 |
| 460.97 | 4.39 | 4.39 |
| 498.59 | 2.83 | 2.83 |
| 492.97 | 2.60 | 2.60 |