Basic Information
ID: ALA3820957
Type: Binding
Description: Inhibition of human recombinant PAK2 assessed as phosphorylation of coumarin labeled FRET peptide substrate at Ser/Thr19 preincubated for 10 mins followed by ATP addition measured after 60 mins by Z'-LYTE assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Serine/threonine-protein kinase PAK 2(ALA4487)
Document: ALA3817726
Inhibition of human recombinant PAK2 assessed as phosphorylation of coumarin labeled FRET peptide substrate at Ser/Thr19 preincubated for 10 mins followed by ATP addition measured after 60 mins by Z'-LYTE assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3820957
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 518.07 | 5.04 | 5.04 |
| 492.97 | 3.22 | 3.22 |
| 463.93 | 3.40 | 3.40 |
| 508.99 | 3.66 | 3.66 |
| 506.99 | 2.86 | 2.86 |
| 570.00 | 3.02 | 3.02 |
| 452.90 | 2.65 | 2.65 |
| 460.97 | 4.39 | 4.39 |
| 498.59 | 2.83 | 2.83 |
| 492.97 | 2.60 | 2.60 |