Basic Information
ID: ALA3821030
Type: Binding
Description: Inhibition of recombinant human CDK4/cyclin D1 using fluoresceinyl-AhxPro-Val-Lys-Arg-Arg-Leu-(3ClPhe)-Gly as substrate incubated for 45 mins by fluorescence polarization assay
Format: BAO_0000223
Organism: Homo sapiens
Target: Cyclin-dependent kinase 4/cyclin D1(ALA1907601)
Document: ALA3817805
Inhibition of recombinant human CDK4/cyclin D1 using fluoresceinyl-AhxPro-Val-Lys-Arg-Arg-Leu-(3ClPhe)-Gly as substrate incubated for 45 mins by fluorescence polarization assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3821030
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 968.13 | -0.55 | -0.55 |
| 735.93 | 1.33 | 1.33 |
| 995.20 | -0.12 | -0.12 |
| 749.96 | 1.33 | 1.33 |
| 664.85 | 2.08 | 2.08 |
| 763.98 | 1.67 | 1.67 |
| 677.90 | 1.32 | 1.32 |
| 677.90 | 1.32 | 1.32 |
| 761.03 | 1.74 | 1.74 |
| 683.92 | 1.38 | 1.38 |
| 697.95 | 1.77 | 1.77 |
| 697.95 | 1.77 | 1.77 |
| 711.98 | 2.16 | 2.16 |
| 652.87 | 2.01 | 2.01 |
| 666.89 | 2.35 | 2.35 |
| 765.96 | 1.03 | 1.03 |
| 794.01 | 1.73 | 1.73 |
| 679.87 | 0.64 | 0.64 |
| 707.92 | 1.33 | 1.33 |
| 750.94 | 2.05 | 2.05 |
| 664.85 | 1.66 | 1.66 |
| 780.97 | 2.06 | 2.06 |