Basic Information
ID: ALA3824522
Type: Functional
Description: Antiinflammatory activity in LPS-induced C57BL/6 mouse sepsis model assessed as inhibition of neutrophils infiltration in lung by measuring MPO activity at 10 mg/kg, iv administered 15 mins prior to LPS challenge measured after 6 hrs in presence of O-dianisidine dihydrochloride relative to control
Organism: Mus musculus
Strain: C57BL/6
Activity Charts
Bioactivity
Activity Types for Assay ALA3824522
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 375.48 | 3.14 | 3.14 |
| 601.63 | 6.56 | 6.56 |
| 578.64 | 5.81 | 5.81 |