Basic Information
ID: ALA3824709
Type: Binding
Description: Inhibition of human ALK using poly[Glu:Tyr] (4:1) as substrate and [gamma-33P]ATP measured after 1 hr
Format: BAO_0000357
Organism: Homo sapiens
Target: ALK tyrosine kinase receptor(ALA4247)
Document: ALA3822358
Inhibition of human ALK using poly[Glu:Tyr] (4:1) as substrate and [gamma-33P]ATP measured after 1 hr: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3824709
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 614.22 | 5.02 | 5.02 |
| 450.35 | 5.04 | 5.04 |
| 529.03 | 5.40 | 5.40 |
| 584.11 | 5.09 | 5.09 |
| 508.97 | 5.06 | 5.06 |
| 432.85 | 4.88 | 4.88 |
| 444.86 | 5.08 | 5.08 |
| 445.85 | 3.97 | 3.97 |
| 480.91 | 4.28 | 4.28 |
| 478.86 | 5.12 | 5.12 |
| 432.93 | 4.81 | 4.81 |
| 530.01 | 5.74 | 5.74 |
| 501.96 | 4.96 | 4.96 |
| 515.98 | 5.35 | 5.35 |
| 487.93 | 4.71 | 4.71 |
| 500.97 | 4.63 | 4.63 |
| 528.98 | 4.54 | 4.54 |
| 501.96 | 4.83 | 4.83 |
| 558.02 | 3.74 | 3.74 |
| 531.00 | 3.99 | 3.99 |
| 515.00 | 5.02 | 5.02 |
| 515.00 | 5.01 | 5.01 |
| 555.06 | 5.80 | 5.80 |
| 555.06 | 5.94 | 5.94 |
| 584.11 | 5.09 | 5.09 |
| 571.06 | 5.17 | 5.17 |
| 598.13 | 5.48 | 5.48 |
| 555.06 | 5.94 | 5.94 |
| 552.02 | 5.66 | 5.66 |
| 499.98 | 5.68 | 5.68 |
| 589.73 | 5.31 | 5.31 |
| 579.69 | 4.45 | 4.45 |
| 567.65 | 4.58 | 4.58 |
| 563.69 | 4.75 | 4.75 |
| 591.70 | 4.64 | 4.64 |
| 612.16 | 5.87 | 5.87 |
| 602.10 | 5.23 | 5.23 |
| 598.13 | 5.40 | 5.40 |
| 598.13 | 5.48 | 5.48 |
| 612.16 | 5.87 | 5.87 |
| 508.07 | 4.84 | 4.84 |
| 633.97 | 5.45 | 5.45 |
| 533.08 | 4.71 | 4.71 |
| 538.10 | 4.85 | 4.85 |
| 551.10 | 3.94 | 3.94 |
| 579.15 | 4.54 | 4.54 |
| 615.20 | 4.09 | 4.09 |
| 550.11 | 5.04 | 5.04 |
| 552.12 | 4.90 | 4.90 |
| 586.16 | 4.25 | 4.25 |