Basic Information
ID: ALA3825052
Type: Binding
Description: Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and incubated for 30 mins by liquid scintillation counting based methyltransferase vapor diffusion assay
Format: BAO_0000249
Organism: Homo sapiens
Target: Isoprenylcysteine carboxyl methyltransferase(ALA4699)
Document: ALA3822411
Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and incubated for 30 mins by liquid scintillation counting based methyltransferase vapor diffusion assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3825052
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 449.62 | 5.36 | 5.36 |
| 325.43 | 4.56 | 4.56 |
| 324.45 | 5.17 | 5.17 |
| 322.43 | 5.22 | 5.22 |
| 324.44 | 4.56 | 4.56 |
| 306.43 | 5.51 | 5.51 |
| 300.40 | 5.45 | 5.45 |
| 226.32 | 3.81 | 3.81 |
| 240.30 | 3.45 | 3.45 |
| 274.38 | 3.41 | 3.41 |
| 256.37 | 4.36 | 4.36 |
| 307.46 | 5.03 | 5.03 |
| 321.49 | 5.38 | 5.38 |