Basic Information
ID: ALA3825096
Type: Binding
Description: Antagonist activity at human iGluA1 receptor flop isoform expressed in CHO-S cells coexpressing TARP gamma-4 assessed as inhibition of glutamate-induced increase in intracellular calcium levels after 2 mins followed by cyclothiazide/glutamate addition by fluorescence imaging plate reader method
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO-S
Target: Glutamate receptor ionotropic, AMPA 1(ALA2009)
Document: ALA3822422
Antagonist activity at human iGluA1 receptor flop isoform expressed in CHO-S cells coexpressing TARP gamma-4 assessed as inhibition of glutamate-induced increase in intracellular calcium levels after 2 mins followed by cyclothiazide/glutamate addition by fluorescence imaging plate reader method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3825096
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 349.39 | 4.44 | 4.44 |
| 283.36 | 3.68 | 3.68 |