Basic Information
ID: ALA3825518
Type: Binding
Description: Inhibition of recombinant human N-terminal His-tagged cytoplasmic c-MET kinase domain (956 to 1390 residues) phosphorylation expressed in baculovirus expression system using Tyr peptide-6 substrate incubated for 1 hr in presence of ATP by Z-Lyte assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3825518
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 138.17 | 0.93 | 0.93 |
| 343.38 | 2.49 | 2.49 |
| 314.34 | 2.91 | 2.91 |
| 344.36 | 2.91 | 2.91 |
| 284.31 | 2.90 | 2.90 |
| 290.31 | 1.83 | 1.83 |
| 362.38 | 1.77 | 1.77 |
| 346.38 | 2.83 | 2.83 |
| 418.24 | 3.56 | 3.56 |
| 346.40 | 3.16 | 3.16 |
| 327.38 | 3.44 | 3.44 |
| 340.34 | 3.34 | 3.34 |
| 360.36 | 2.62 | 2.62 |
| 300.31 | 2.60 | 2.60 |
| 330.34 | 2.61 | 2.61 |
| 374.39 | 2.92 | 2.92 |
| 344.36 | 2.91 | 2.91 |
| 313.35 | 2.78 | 2.78 |
| 343.38 | 2.79 | 2.79 |
| 328.36 | 3.30 | 3.30 |
| 358.39 | 3.30 | 3.30 |
| 328.32 | 2.93 | 2.93 |
| 358.35 | 2.94 | 2.94 |
| 358.39 | 3.22 | 3.22 |
| 358.39 | 3.22 | 3.22 |
| 388.42 | 3.23 | 3.23 |
| 388.42 | 3.23 | 3.23 |
| 359.38 | 2.50 | 2.50 |
| 358.39 | 3.30 | 3.30 |
| 388.42 | 3.31 | 3.31 |
| 386.40 | 3.39 | 3.39 |
| 330.34 | 2.87 | 2.87 |
| 343.38 | 2.79 | 2.79 |
| 343.38 | 2.79 | 2.79 |
| 327.38 | 3.17 | 3.17 |
| 327.38 | 3.17 | 3.17 |
| 329.35 | 2.49 | 2.49 |
| 313.35 | 2.78 | 2.78 |
| 360.36 | 2.88 | 2.88 |
| 356.37 | 3.38 | 3.38 |
| 390.39 | 2.89 | 2.89 |
| 404.42 | 2.93 | 2.93 |
| 374.39 | 2.92 | 2.92 |
| 344.37 | 2.19 | 2.19 |
| 314.34 | 2.18 | 2.18 |
| 300.31 | 2.13 | 2.13 |
| 330.34 | 2.14 | 2.14 |