Basic Information
ID: ALA3825933
Type: Binding
Description: Inhibition of Pseudomonas aeruginosa recombinant His-tagged CFTR inhibitory factor expressed in expressed in Top10 Escherichia coli cells assessed as formation of 6-methoxy-2-naphthaldehyde preincubated for 5 mins followed by addition of CMNGC as substrate measured for 10 mins in presence of BSA by fluorescent-based assay
Organism: Pseudomonas aeruginosa
Activity Charts
Bioactivity
Activity Types for Assay ALA3825933
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 487.14 | 5.25 | 5.25 |
| 401.10 | 5.42 | 5.42 |
| 431.08 | 5.74 | 5.74 |
| 443.14 | 5.79 | 5.79 |
| 457.16 | 6.18 | 6.18 |
| 515.20 | 5.72 | 5.72 |
| 501.17 | 5.64 | 5.64 |
| 529.23 | 6.11 | 6.11 |
| 499.20 | 6.02 | 6.02 |
| 529.23 | 6.03 | 6.03 |
| 426.30 | 5.51 | 5.51 |
| 391.85 | 4.85 | 4.85 |
| 384.21 | 4.38 | 4.38 |
| 463.11 | 5.15 | 5.15 |
| 510.11 | 4.99 | 4.99 |
| 452.21 | 5.40 | 5.40 |
| 408.24 | 4.36 | 4.36 |
| 463.11 | 5.15 | 5.15 |
| 402.28 | 6.51 | 6.51 |
| 446.29 | 6.21 | 6.21 |
| 445.30 | 5.61 | 5.61 |
| 445.30 | 5.61 | 5.61 |
| 427.29 | 6.38 | 6.38 |
| 427.29 | 6.38 | 6.38 |
| 459.33 | 5.87 | 5.87 |
| 460.32 | 6.00 | 6.00 |
| 459.33 | 6.47 | 6.47 |
| 444.31 | 6.71 | 6.71 |
| 481.36 | 5.15 | 5.15 |