Assay Report Card

Basic Information

ID: ALA3826030

Type: Binding

Description: Inhibition of PTP1B in rat L6 cells assessed as increase in insulin-stimulated 2-NBDG uptake at 10 uM preincubated for 4 hrs followed by insulin stimulation for 10 mins and subsequent addition of 2-NBDG measured after 30 mins by fluorescence assay relative to control

Organism: Rattus norvegicus

Cell type: L6

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
618.733.743.74
680.804.844.84