Assay Report Card

Basic Information

ID: ALA3829093

Type: Binding

Description: Inhibition of recombinant Staphylococcus aureus DHFR expressed in Escherichia coli BL21(DE3) cells assessed as reduction in NADPH oxidation using dihydrofolate as substrate preincubated for 5 mins followed by substrate addition

Organism: Staphylococcus aureus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
290.321.261.26
402.453.173.17
516.483.173.17
402.453.173.17
516.483.173.17
476.533.733.73
476.533.733.73
416.483.733.73
416.483.733.73