Basic Information
ID: ALA3829127
Type: Binding
Description: Inhibition of N-terminal GST-tagged human TNKS-2 (849 to 1166 residues) expressed in in insect sf21 cells at 10 nM preincubated for 2 hrs followed by substrate addition measured after 30 mins
Organism: Homo sapiens
Cell type: Sf21
Activity Charts
Bioactivity
Activity Types for Assay ALA3829127
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 240.24 | 3.14 | 3.14 |
| 252.27 | 3.02 | 3.02 |
| 254.25 | 2.41 | 2.41 |
| 253.26 | 2.29 | 2.29 |
| 236.27 | 3.31 | 3.31 |
| 297.27 | 2.92 | 2.92 |
| 281.27 | 3.22 | 3.22 |
| 252.27 | 3.01 | 3.01 |
| 238.25 | 2.71 | 2.71 |
| 283.24 | 2.62 | 2.62 |
| 251.29 | 2.89 | 2.89 |
| 282.30 | 3.02 | 3.02 |
| 266.30 | 3.32 | 3.32 |
| 320.27 | 4.03 | 4.03 |
| 222.25 | 3.00 | 3.00 |
| 252.27 | 3.01 | 3.01 |
| 267.29 | 2.59 | 2.59 |
| 300.31 | 2.06 | 2.06 |
| 270.29 | 2.05 | 2.05 |
| 254.29 | 2.35 | 2.35 |
| 304.27 | 4.33 | 4.33 |
| 306.24 | 3.73 | 3.73 |
| 315.29 | 1.95 | 1.95 |
| 256.69 | 3.24 | 3.24 |
| 267.24 | 2.50 | 2.50 |
| 270.29 | 2.05 | 2.05 |
| 301.14 | 3.35 | 3.35 |
| 290.24 | 3.61 | 3.61 |
| 399.45 | 4.32 | 4.32 |
| 286.72 | 3.25 | 3.25 |
| 315.17 | 3.66 | 3.66 |
| 254.26 | 3.04 | 3.04 |
| 270.72 | 3.55 | 3.55 |
| 250.30 | 3.21 | 3.21 |
| 272.69 | 2.95 | 2.95 |
| 346.23 | 2.36 | 2.36 |
| 238.25 | 2.30 | 2.30 |
| 236.27 | 2.90 | 2.90 |
| 237.26 | 2.17 | 2.17 |
| 385.42 | 4.02 | 4.02 |
| 266.30 | 2.91 | 2.91 |
| 331.17 | 3.36 | 3.36 |
| 270.26 | 2.74 | 2.74 |
| 252.27 | 2.60 | 2.60 |
| 317.14 | 3.06 | 3.06 |
| 256.24 | 2.43 | 2.43 |
| 240.26 | 2.04 | 2.04 |
| 254.29 | 2.35 | 2.35 |
| 308.26 | 3.06 | 3.06 |
| 274.71 | 2.69 | 2.69 |
| 319.16 | 2.80 | 2.80 |
| 258.25 | 2.18 | 2.18 |
| 285.26 | 1.95 | 1.95 |
| 255.28 | 1.62 | 1.62 |
| 268.32 | 2.65 | 2.65 |
| 322.29 | 3.37 | 3.37 |
| 284.31 | 2.35 | 2.35 |
| 288.73 | 3.00 | 3.00 |
| 333.18 | 3.11 | 3.11 |
| 272.28 | 2.49 | 2.49 |
| 299.29 | 2.25 | 2.25 |
| 269.30 | 1.93 | 1.93 |
| 284.31 | 2.35 | 2.35 |
| 338.29 | 3.07 | 3.07 |
| 304.73 | 2.70 | 2.70 |
| 349.18 | 2.81 | 2.81 |
| 288.28 | 2.19 | 2.19 |
| 285.30 | 1.63 | 1.63 |
| 250.30 | 3.21 | 3.21 |
| 250.30 | 3.21 | 3.21 |
| 312.33 | 2.62 | 2.62 |
| 403.44 | 3.46 | 3.46 |
| 417.47 | 3.77 | 3.77 |
| 475.50 | 4.04 | 4.04 |
| 332.20 | 2.05 | 2.05 |
| 422.28 | 2.07 | 2.07 |
| 228.28 | 2.65 | 2.65 |