Basic Information
ID: ALA3829147
Type: Binding
Description: Displacement of biotinylated TN14003 from CXCR4 CXCL12 binding domain in human MDA-MB-231 cells preincubated for 10 mins followed by biotinylated TN14003 addition measured after 30 mins using streptavidin-conjugated rhodamine by fluorescence microscopic analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MDA-MB-231
Target: C-X-C chemokine receptor type 4(ALA2107)
Document: ALA3826889
Displacement of biotinylated TN14003 from CXCR4 CXCL12 binding domain in human MDA-MB-231 cells preincubated for 10 mins followed by biotinylated TN14003 addition measured after 30 mins using streptavidin-conjugated rhodamine by fluorescence microscopic analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3829147
EC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 502.80 | 0.42 | 0.42 |
| 272.44 | 3.66 | 3.66 |
| 316.45 | 4.96 | 4.96 |
| 353.42 | 4.63 | 4.63 |
| 414.38 | 5.65 | 5.65 |
| 414.38 | 5.65 | 5.65 |
| 381.47 | 4.62 | 4.62 |
| 381.47 | 4.62 | 4.62 |
| 381.47 | 4.62 | 4.62 |
| 405.54 | 4.36 | 4.36 |
| 373.54 | 5.13 | 5.13 |
| 425.62 | 5.91 | 5.91 |
| 347.47 | 3.14 | 3.14 |
| 347.47 | 3.14 | 3.14 |
| 347.47 | 3.14 | 3.14 |
| 244.38 | 2.88 | 2.88 |
| 276.38 | 1.35 | 1.35 |
| 352.43 | 5.24 | 5.24 |
| 413.39 | 6.26 | 6.26 |
| 413.39 | 6.26 | 6.26 |
| 380.48 | 5.23 | 5.23 |
| 380.48 | 5.23 | 5.23 |
| 380.48 | 5.23 | 5.23 |
| 404.55 | 4.97 | 4.97 |
| 372.56 | 5.73 | 5.73 |
| 424.63 | 6.51 | 6.51 |
| 346.48 | 3.74 | 3.74 |
| 346.48 | 3.74 | 3.74 |
| 346.48 | 3.74 | 3.74 |
| 245.37 | 2.27 | 2.27 |
| 273.42 | 3.05 | 3.05 |
| 277.37 | 0.75 | 0.75 |
| 317.44 | 4.35 | 4.35 |