Assay Report Card

Basic Information

ID: ALA3830152

Type: Functional

Description: Attenuation of methicillin-resistant Staphylococcus aureus USA400 MW2 virulence in BALB/c mouse systemic infection model assessed as decrease in bacterial burden in liver at 200 mg/kg, ip administered every 12 hrs for 108 hrs followed by bacterial challenge after first 12 hrs of compound dosing measured 5 days post infection

Organism: Staphylococcus aureus

Strain: MW2 USA400

Tissue: Liver

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
500.633.193.19
371.955.115.11