Basic Information
ID: ALA3853443
Type: Binding
Description: Inhibition of human C-terminal eGFP-tagged URAT1 long isoform expressed in CHO cells assessed as decrease in [14C]-uric acid uptake preincubated for 15 mins followed by [14C]-uric acid addition and incubated in dark for 3 hrs by scintillation counting method
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA3853443
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 428.83 | 4.21 | 4.21 |
| 394.39 | 3.56 | 3.56 |
| 394.39 | 3.56 | 3.56 |
| 412.38 | 3.70 | 3.70 |
| 428.83 | 4.21 | 4.21 |
| 412.38 | 3.70 | 3.70 |
| 428.83 | 4.21 | 4.21 |
| 421.81 | 4.48 | 4.48 |
| 411.83 | 3.47 | 3.47 |
| 410.84 | 4.07 | 4.07 |
| 411.83 | 3.47 | 3.47 |
| 429.82 | 3.61 | 3.61 |
| 410.84 | 4.07 | 4.07 |
| 411.83 | 3.47 | 3.47 |
| 405.36 | 3.96 | 3.96 |
| 411.83 | 3.47 | 3.47 |
| 405.36 | 3.96 | 3.96 |
| 421.81 | 4.48 | 4.48 |
| 433.85 | 3.83 | 3.83 |
| 387.37 | 3.82 | 3.82 |
| 413.85 | 3.41 | 3.41 |
| 416.87 | 4.13 | 4.13 |
| 417.86 | 3.53 | 3.53 |
| 416.87 | 4.13 | 4.13 |
| 417.86 | 3.53 | 3.53 |