Basic Information
ID: ALA3853552
Type: Binding
Description: Inhibition of human C-terminal eGFP-tagged URAT1 long isoform expressed in CHO cells assessed as decrease in [14C]-uric acid uptake preincubated for 15 mins followed by [14C]-uric acid addition and incubated in dark for 3 hrs by scintillation counting method
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA3853552
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 360.74 | 4.03 | 4.03 |
| 332.30 | 2.91 | 2.91 |
| 387.28 | 4.66 | 4.66 |
| 360.74 | 4.03 | 4.03 |
| 394.30 | 4.40 | 4.40 |
| 332.30 | 2.91 | 2.91 |
| 360.74 | 4.03 | 4.03 |
| 319.28 | 3.65 | 3.65 |
| 316.30 | 3.21 | 3.21 |
| 322.77 | 3.02 | 3.02 |
| 317.76 | 2.88 | 2.88 |
| 332.30 | 2.91 | 2.91 |
| 360.74 | 4.03 | 4.03 |
| 370.27 | 3.92 | 3.92 |
| 370.27 | 3.92 | 3.92 |
| 332.30 | 2.91 | 2.91 |
| 327.19 | 3.67 | 3.67 |
| 326.30 | 3.38 | 3.38 |
| 317.76 | 2.88 | 2.88 |
| 306.77 | 3.32 | 3.32 |
| 326.30 | 3.38 | 3.38 |
| 376.74 | 3.91 | 3.91 |
| 360.74 | 4.03 | 4.03 |
| 337.27 | 3.78 | 3.78 |
| 316.30 | 3.21 | 3.21 |
| 367.30 | 4.11 | 4.11 |
| 327.19 | 3.67 | 3.67 |
| 385.29 | 4.40 | 4.40 |
| 326.30 | 3.38 | 3.38 |
| 352.34 | 4.05 | 4.05 |
| 306.77 | 3.32 | 3.32 |
| 394.30 | 4.40 | 4.40 |
| 360.74 | 4.03 | 4.03 |
| 360.74 | 4.03 | 4.03 |
| 316.30 | 3.21 | 3.21 |
| 381.17 | 3.66 | 3.66 |