Activation of beta-hexosaminidase A p.G269S/c.1278insTACT mutant in human Tay-Sachs disease patient skin fibroblasts assessed as 4-MU liberation at 0....

Basic Information

ID: ALA3853694

Type: Binding

Description: Activation of beta-hexosaminidase A p.G269S/c.1278insTACT mutant in human Tay-Sachs disease patient skin fibroblasts assessed as 4-MU liberation at 0.2 uM using 4-MU-N-acetyl-beta-D-glucosaminide-6-sulfate sodium salt as substrate after 4 days by fluorescence assay relative to control

Format: BAO_0000019

Organism: Homo sapiens

Target:  Unchecked(ALA612545)

Document:  ALA3853269

Activation of beta-hexosaminidase A p.G269S/c.1278insTACT mutant in human Tay-Sachs disease patient skin fibroblasts assessed as 4-MU liberation at 0.2 uM using 4-MU-N-acetyl-beta-D-glucosaminide-6-sulfate sodium salt as substrate after 4 days by fluorescence assay relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
375.540.120.12