Basic Information
ID: ALA3854652
Type: Binding
Description: Inhibition of USP1/UAF1 complex in human H596 cells assessed as potentiation of cisplatin-induced cell killing by measuring cisplatin GI50 at 1:4 cisplatin to compound ratio pretreated for 48 hrs followed by addition of fresh growth medium measured after 5 to 10 days by colony forming assay (Rvb = 486 nM)
Organism: Homo sapiens
Cell type: H596
Activity Charts
Bioactivity
Activity Types for Assay ALA3854652
GI50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.49 | 4.77 | 4.77 |