Basic Information
ID: ALA3854709
Type: Binding
Description: Activation of recombinant human AMPK alpha1/beta1/gamma1 using Cy5-labelled SAMS as substrate assessed as protection from Thr172 residue dephosphorylation preincubated for 15 mins followed by incubation with PP2a for 60 mins measured 60 mins post okadaic acid/Cy5-labelled SAMS and ATP addition by TR-FRET assay
Format: BAO_0000223
Organism: Homo sapiens
Target: AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1(ALA2111345)
Document: ALA3853317
Activation of recombinant human AMPK alpha1/beta1/gamma1 using Cy5-labelled SAMS as substrate assessed as protection from Thr172 residue dephosphorylation preincubated for 15 mins followed by incubation with PP2a for 60 mins measured 60 mins post okadaic acid/Cy5-labelled SAMS and ATP addition by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3854709
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 347.22 | -1.86 | -1.86 |
| 341.79 | 4.56 | 4.56 |
| 363.80 | 5.56 | 5.56 |
| 301.73 | 4.20 | 4.20 |
| 301.73 | 3.68 | 3.68 |
| 268.27 | 2.94 | 2.94 |
| 302.72 | 3.59 | 3.59 |