Assay Report Card

Basic Information

ID: ALA3854710

Type: Binding

Description: Activation of recombinant human AMPK alpha1/beta1/gamma1 using Cy5-labelled SAMS as substrate assessed as protection from Thr172 residue dephosphorylation preincubated for 15 mins followed by incubation with PP2a for 60 mins measured 60 mins post okadaic acid/Cy5-labelled SAMS and ATP addition by TR-FRET assay relative to AMP

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
347.22-1.86-1.86
341.794.564.56
363.805.565.56
301.734.204.20
301.733.683.68
268.272.942.94
302.723.593.59
387.443.703.70