Basic Information
ID: ALA3854801
Type: Binding
Description: Inhibition of Alexa647 tracer binding to full length recombinant human His-tagged CDK8/cyclin C expressed in Baculovirus expression system preincubated for 20 mins followed by tracer addition and incubated in dark for 60 mins by FRET-based Lanthascreen assay
Format: BAO_0000019
Organism: Homo sapiens
Target: CDK8/Cyclin C(ALA3038474)
Document: ALA3853318
Inhibition of Alexa647 tracer binding to full length recombinant human His-tagged CDK8/cyclin C expressed in Baculovirus expression system preincubated for 20 mins followed by tracer addition and incubated in dark for 60 mins by FRET-based Lanthascreen assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3854801
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 316.39 | 2.43 | 2.43 |
| 354.84 | 4.24 | 4.24 |
| 312.40 | 3.08 | 3.08 |
| 340.81 | 3.90 | 3.90 |
| 330.39 | 3.22 | 3.22 |
| 340.81 | 3.78 | 3.78 |
| 340.81 | 3.90 | 3.90 |
| 340.81 | 3.67 | 3.67 |
| 325.80 | 4.19 | 4.19 |
| 346.84 | 3.73 | 3.73 |
| 346.84 | 3.73 | 3.73 |
| 355.83 | 3.74 | 3.74 |
| 385.26 | 3.88 | 3.88 |
| 340.81 | 3.90 | 3.90 |
| 339.83 | 4.27 | 4.27 |
| 340.81 | 3.43 | 3.43 |
| 339.83 | 4.50 | 4.50 |
| 310.33 | 2.87 | 2.87 |
| 325.80 | 4.11 | 4.11 |
| 346.84 | 3.73 | 3.73 |
| 368.87 | 3.65 | 3.65 |
| 330.41 | 2.99 | 2.99 |
| 324.36 | 3.26 | 3.26 |
| 338.39 | 3.65 | 3.65 |