Basic Information
ID: ALA3854816
Type: Binding
Description: Inhibition of Alexa647 tracer binding to full length recombinant human His-tagged CDK8/cyclin C expressed in Baculovirus expression system at 1 uM preincubated for 20 mins followed by tracer addition and incubated in dark for 60 mins by FRET-based Lanthascreen assay relative to control
Format: BAO_0000019
Organism: Homo sapiens
Target: CDK8/Cyclin C(ALA3038474)
Document: ALA3853318
Inhibition of Alexa647 tracer binding to full length recombinant human His-tagged CDK8/cyclin C expressed in Baculovirus expression system at 1 uM preincubated for 20 mins followed by tracer addition and incubated in dark for 60 mins by FRET-based Lanthascreen assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3854816
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 354.84 | 4.24 | 4.24 |
| 340.81 | 3.78 | 3.78 |
| 385.26 | 3.88 | 3.88 |
| 340.81 | 3.43 | 3.43 |
| 310.33 | 2.87 | 2.87 |
| 324.36 | 3.26 | 3.26 |
| 338.39 | 3.65 | 3.65 |