Basic Information
ID: ALA3854864
Type: Binding
Description: Irreversible inhibition of GST-tagged ERBB2 (unknown origin) (Ile-675 to Val-1256 residues) expressed in baculovirus infected Sf9 insect cells assessed as reduction in Glu/Tyr copolymer phosphorylation after 6 mins by ELISA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Receptor protein-tyrosine kinase erbB-2(ALA1824)
Document: ALA3853319
Irreversible inhibition of GST-tagged ERBB2 (unknown origin) (Ile-675 to Val-1256 residues) expressed in baculovirus infected Sf9 insect cells assessed as reduction in Glu/Tyr copolymer phosphorylation after 6 mins by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3854864
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 446.91 | 4.28 | 4.28 |
| 558.87 | 4.39 | 4.39 |
| 469.95 | 5.16 | 5.16 |
| 577.69 | 5.39 | 5.39 |
| 596.71 | 5.55 | 5.55 |
| 466.55 | 5.15 | 5.15 |
| 570.68 | 5.02 | 5.02 |
| 453.55 | 5.29 | 5.29 |
| 533.01 | 5.73 | 5.73 |
| 563.66 | 5.00 | 5.00 |
| 589.74 | 6.93 | 6.93 |
| 576.71 | 4.91 | 4.91 |
| 494.60 | 3.50 | 3.50 |
| 455.93 | 3.30 | 3.30 |
| 553.67 | 4.49 | 4.49 |
| 547.66 | 5.76 | 5.76 |
| 478.53 | 3.93 | 3.93 |
| 429.48 | 4.70 | 4.70 |
| 374.80 | 4.52 | 4.52 |
| 440.91 | 4.54 | 4.54 |
| 494.60 | 4.96 | 4.96 |
| 521.63 | 5.23 | 5.23 |
| 612.71 | 4.79 | 4.79 |
| 428.49 | 5.31 | 5.31 |
| 601.73 | 4.32 | 4.32 |
| 605.11 | 5.89 | 5.89 |
| 590.73 | 5.35 | 5.35 |
| 561.69 | 6.15 | 6.15 |
| 414.47 | 5.52 | 5.52 |
| 452.52 | 5.13 | 5.13 |
| 504.60 | 4.76 | 4.76 |
| 478.56 | 4.22 | 4.22 |
| 485.99 | 5.79 | 5.79 |
| 577.73 | 6.78 | 6.78 |
| 588.69 | 4.40 | 4.40 |
| 487.96 | 4.62 | 4.62 |
| 442.88 | 3.39 | 3.39 |
| 509.61 | 6.15 | 6.15 |
| 551.65 | 4.85 | 4.85 |
| 454.53 | 4.69 | 4.69 |
| 480.93 | 6.10 | 6.10 |
| 576.07 | 6.73 | 6.73 |
| 361.41 | 4.21 | 4.21 |
| 441.49 | 5.33 | 5.33 |
| 465.56 | 4.34 | 4.34 |
| 400.85 | 3.62 | 3.62 |
| 452.52 | 5.13 | 5.13 |
| 439.52 | 3.81 | 3.81 |
| 606.73 | 4.54 | 4.54 |
| 477.55 | 4.53 | 4.53 |
| 590.73 | 5.35 | 5.35 |
| 451.53 | 5.73 | 5.73 |
| 440.51 | 4.62 | 4.62 |
| 524.63 | 5.34 | 5.34 |
| 501.57 | 4.92 | 4.92 |
| 506.97 | 5.20 | 5.20 |
| 572.69 | 5.16 | 5.16 |