Basic Information
ID: ALA3854871
Type: Binding
Description: Irreversible inhibition of ERBB1 autophosphorylation in EGF-stimulated human A431 cells assessed as length of drug exposure time required to provide 100% inhibition treated with compound followed by stimulation with EGF by sandwich ELISA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: A-431
Target: Epidermal growth factor receptor erbB1(ALA203)
Document: ALA3853319
Irreversible inhibition of ERBB1 autophosphorylation in EGF-stimulated human A431 cells assessed as length of drug exposure time required to provide 100% inhibition treated with compound followed by stimulation with EGF by sandwich ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3854871
TIME
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 558.87 | 4.39 | 4.39 |
| 469.95 | 5.16 | 5.16 |
| 596.71 | 5.55 | 5.55 |
| 563.66 | 5.00 | 5.00 |
| 576.71 | 4.91 | 4.91 |
| 547.66 | 5.76 | 5.76 |
| 440.91 | 4.54 | 4.54 |
| 521.63 | 5.23 | 5.23 |
| 612.71 | 4.79 | 4.79 |
| 601.73 | 4.32 | 4.32 |
| 590.73 | 5.35 | 5.35 |
| 561.69 | 6.15 | 6.15 |
| 485.99 | 5.79 | 5.79 |
| 577.73 | 6.78 | 6.78 |
| 588.69 | 4.40 | 4.40 |
| 572.69 | 5.16 | 5.16 |