Basic Information
ID: ALA3854930
Type: Binding
Description: Inhibition of human COT (66 to 395 residues) expressed in Sf21 cells using 5-Fluo-Ahx-AGAGSGQLIDSNleANSFVGTR-NH2 as substrate after 60 mins by caliper microfluidic mobility shift assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf21
Target: Mitogen-activated protein kinase kinase kinase 8(ALA4899)
Document: ALA3853320
Inhibition of human COT (66 to 395 residues) expressed in Sf21 cells using 5-Fluo-Ahx-AGAGSGQLIDSNleANSFVGTR-NH2 as substrate after 60 mins by caliper microfluidic mobility shift assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3854930
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 482.20 | 2.47 | 2.47 |
| 522.64 | 4.77 | 4.77 |
| 507.62 | 4.99 | 4.99 |
| 320.74 | 3.50 | 3.50 |
| 373.42 | 5.18 | 5.18 |
| 400.89 | 6.02 | 6.02 |
| 376.42 | 4.82 | 4.82 |
| 379.45 | 5.25 | 5.25 |
| 366.43 | 4.80 | 4.80 |
| 516.61 | 4.71 | 4.71 |
| 527.68 | 5.44 | 5.44 |
| 362.40 | 4.51 | 4.51 |
| 521.65 | 5.38 | 5.38 |
| 352.36 | 3.24 | 3.24 |
| 366.45 | 5.37 | 5.37 |
| 393.48 | 5.55 | 5.55 |
| 363.38 | 3.91 | 3.91 |
| 367.44 | 4.76 | 4.76 |
| 516.61 | 4.71 | 4.71 |
| 516.61 | 4.71 | 4.71 |
| 369.41 | 3.97 | 3.97 |
| 363.38 | 3.91 | 3.91 |
| 368.43 | 4.57 | 4.57 |
| 369.43 | 3.84 | 3.84 |
| 376.42 | 4.82 | 4.82 |