Basic Information
ID: ALA3854931
Type: Binding
Description: Inhibition of MEK/ERK signaling pathway in TNFalpha-stimulated human A431 cells transfected with COT siRNA assessed as reduction in ERK1/2 phosphorylation incubated for 60 mins followed by stimulation with TNFalpha for 10 mins by Western blot analysis
Organism: Homo sapiens
Cell type: A-431
Activity Charts
Bioactivity
Activity Types for Assay ALA3854931
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 482.20 | 2.47 | 2.47 |
| 379.45 | 5.25 | 5.25 |