Basic Information
ID: ALA3854934
Type: Binding
Description: Inhibition of COT in LPS-stimulated human PBMC assessed as reduction in TNFalpha release incubated for 1 hr followed by stimulation with LPS for 4 hrs by HTRF assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3854934
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 522.64 | 4.77 | 4.77 |
| 507.62 | 4.99 | 4.99 |
| 379.45 | 5.25 | 5.25 |
| 516.61 | 4.71 | 4.71 |
| 527.68 | 5.44 | 5.44 |
| 521.65 | 5.38 | 5.38 |
| 516.61 | 4.71 | 4.71 |
| 516.61 | 4.71 | 4.71 |