ID: ALA3855007
Type: ADME
Description: Drug metabolism in Sprague-Dawley rat liver microsomes assessed as glucuronic acid conjugate 1-(2-(1-morpholinopropan-2-ylamino)benzo[d]thiazol-6-yl)-8-(thiophen-2-yl)-1H-imidazo[4,5-c][1,7]naphthyridin-4(5H)-one metabolite formation at 5 uM after 1 hr in presence of NADPH by HPLC/MS analysis
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Liver
Bioactivity
Activity Types for Assay ALA3855007
Drug metabolism
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
516.61 | 4.71 | 4.71 |