Basic Information
ID: ALA3855162
Type: Binding
Description: Inhibition of Lassa virus N-terminal His-tagged NP exonuclease domain (342 to 569 residues) expressed in Escherichia coli Tuner (DE3) using FAM-labeled 20-nucleotide ssRNA preincubated for 10 mins followed by substrate addition measured after 60 mins by PAGE based autoradiography
Organism: Mammarenavirus lassaense
Activity Charts
Bioactivity
Activity Types for Assay ALA3855162
INH
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 422.35 | 2.45 | 2.45 |
| 192.12 | -1.25 | -1.25 |
| 495.28 | 5.20 | 5.20 |
| 396.36 | 3.70 | 3.70 |
| 393.48 | 4.95 | 4.95 |
| 206.16 | 1.77 | 1.77 |
| 393.21 | ||
| 193.27 | -0.64 | -0.64 |
| 518.44 | 4.31 | 4.31 |