Basic Information
ID: ALA3856822
Type: Binding
Description: Inhibition of recombinant Coxsackievirus B3 3C protease expressed in Escherichia coli BL21 (DE3) preincubated for 5 mins followed by addition of NMA-EALFQGPPVK-DNP-rrr-NH2 as substrate measured up to 2 hrs by FRET-based enzyme assay
Organism: Coxsackievirus B3
Activity Charts
Bioactivity
Activity Types for Assay ALA3856822
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 256.26 | 1.86 | 1.86 |
| 240.26 | 2.16 | 2.16 |
| 256.26 | 1.86 | 1.86 |
| 256.26 | 1.86 | 1.86 |
| 272.26 | 1.57 | 1.57 |
| 256.26 | 1.86 | 1.86 |
| 240.26 | 2.16 | 2.16 |
| 332.36 | 1.65 | 1.65 |
| 292.27 | 1.38 | 1.38 |
| 302.33 | 1.56 | 1.56 |
| 428.49 | 3.76 | 3.76 |
| 240.26 | 2.16 | 2.16 |
| 314.34 | 2.28 | 2.28 |
| 353.17 | 2.00 | 2.00 |
| 433.46 | 1.77 | 1.77 |
| 286.29 | 1.50 | 1.50 |
| 288.26 | 1.27 | 1.27 |
| 346.36 | 2.81 | 2.81 |
| 344.37 | 2.37 | 2.37 |
| 351.16 | 2.33 | 2.33 |
| 433.44 | 2.53 | 2.53 |
| 318.30 | 2.03 | 2.03 |
| 431.45 | 2.10 | 2.10 |
| 256.26 | 1.86 | 1.86 |
| 288.30 | 1.17 | 1.17 |
| 272.26 | 1.57 | 1.57 |
| 304.30 | 0.87 | 0.87 |
| 328.37 | 2.67 | 2.67 |
| 308.72 | 1.89 | 1.89 |
| 330.38 | 2.34 | 2.34 |
| 290.25 | 1.71 | 1.71 |
| 274.28 | 1.24 | 1.24 |
| 350.35 | 0.97 | 0.97 |
| 300.31 | 1.89 | 1.89 |
| 348.37 | 2.48 | 2.48 |
| 330.34 | 1.98 | 1.98 |
| 302.29 | 1.20 | 1.20 |
| 302.36 | 1.85 | 1.85 |
| 435.45 | 2.20 | 2.20 |
| 306.71 | 2.22 | 2.22 |
| 541.54 | 1.87 | 1.87 |
| 430.50 | 3.43 | 3.43 |
| 332.33 | 2.42 | 2.42 |
| 304.28 | 1.64 | 1.64 |
| 306.29 | 1.31 | 1.31 |
| 290.27 | 0.94 | 0.94 |
| 334.35 | 2.09 | 2.09 |
| 346.38 | 2.04 | 2.04 |
| 318.33 | 1.26 | 1.26 |
| 274.28 | 1.24 | 1.24 |
| 302.36 | 1.85 | 1.85 |
| 374.39 | 2.33 | 2.33 |
| 543.55 | 1.54 | 1.54 |
| 316.36 | 1.95 | 1.95 |
| 372.38 | 2.66 | 2.66 |
| 316.31 | 1.59 | 1.59 |
| 320.32 | 1.70 | 1.70 |
| 224.26 | 2.45 | 2.45 |
| 352.37 | 0.64 | 0.64 |