Basic Information
ID: ALA3857946
Type: Binding
Description: Inhibition of HMG-CoA reductase in rat liver microsomes assessed as reduction in [14C]-HMG-CoA conversion to [14C]-mevalonic acid after 15 mins by column filtration method
Format: BAO_0000221
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsomes
Target: HMG-CoA reductase(ALA3247)
Document: ALA3856219
Inhibition of HMG-CoA reductase in rat liver microsomes assessed as reduction in [14C]-HMG-CoA conversion to [14C]-mevalonic acid after 15 mins by column filtration method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3857946
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 421.47 | 4.52 | 4.52 |
| 423.48 | 4.76 | 4.76 |