Basic Information
ID: ALA3857976
Type: ADME
Description: Stability in mouse liver microsomes assessed as oxidative metabolism by measuring drug recovery at 10 uM preincubated for 10 mins followed by NADPH addition measured after 30 mins by liquid chromatographic method
Format: BAO_0000221
Organism: Mus musculus
Tissue: Liver
Target: ADMET(ALA612558)
Document: ALA3856221
Stability in mouse liver microsomes assessed as oxidative metabolism by measuring drug recovery at 10 uM preincubated for 10 mins followed by NADPH addition measured after 30 mins by liquid chromatographic method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3857976
Drug recovery
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 535.71 | 4.69 | 4.69 |
| 441.62 | 5.35 | 5.35 |
| 466.63 | 5.22 | 5.22 |
| 472.63 | 4.76 | 4.76 |
| 472.63 | 4.76 | 4.76 |
| 472.63 | 4.76 | 4.76 |
| 474.61 | 3.60 | 3.60 |
| 474.61 | 3.60 | 3.60 |
| 474.61 | 3.60 | 3.60 |
| 485.67 | 5.92 | 5.92 |
| 530.57 | 4.75 | 4.75 |
| 511.59 | 5.22 | 5.22 |
| 614.83 | 5.46 | 5.46 |
| 514.65 | 5.37 | 5.37 |
| 469.59 | 3.47 | 3.47 |
| 584.80 | 5.45 | 5.45 |
| 509.63 | 5.23 | 5.23 |
| 469.59 | 3.47 | 3.47 |
| 468.60 | 4.07 | 4.07 |
| 501.67 | 4.72 | 4.72 |
| 487.58 | 3.60 | 3.60 |
| 444.58 | 3.59 | 3.59 |
| 496.66 | 5.23 | 5.23 |
| 485.67 | 5.92 | 5.92 |
| 512.58 | 4.61 | 4.61 |
| 455.65 | 5.91 | 5.91 |
| 487.58 | 3.60 | 3.60 |
| 512.58 | 4.61 | 4.61 |
| 600.80 | 5.07 | 5.07 |
| 455.65 | 5.74 | 5.74 |
| 455.65 | 5.91 | 5.91 |
| 498.72 | 5.41 | 5.41 |
| 510.68 | 5.79 | 5.79 |
| 530.57 | 4.75 | 4.75 |
| 570.78 | 5.06 | 5.06 |
| 455.65 | 5.74 | 5.74 |
| 531.70 | 5.34 | 5.34 |
| 531.70 | 4.73 | 4.73 |
| 501.67 | 5.34 | 5.34 |
| 510.68 | 5.79 | 5.79 |