Assay Report Card

Basic Information

ID: ALA3858209

Type: Binding

Description: Induction of P-gp-mediated lysosomal membrane permeabilization in human KBV1 cells over expressing P-gp assessed as cathepsin D release from lysosome to cytosol at 25 uM after 24 hrs by TexasRed staining based immunofluorescence microscopic analysis

Organism: Homo sapiens

Cell type: KBV1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
284.392.272.27
353.503.373.37