Basic Information
ID: ALA3858211
Type: Binding
Description: Induction of P-gp-mediated lysosomal membrane permeabilization in human KBV1 cells over expressing P-gp assessed as cathepsin D release from lysosome to cytosol at 25 uM after 24 hrs in presence of P-gp inhibitor elacridar by TexasRed staining based immunofluorescence microscopic analysis
Organism: Homo sapiens
Cell type: KBV1
Activity Charts
Bioactivity
Activity Types for Assay ALA3858211
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 284.39 | 2.27 | 2.27 |
| 353.50 | 3.37 | 3.37 |