Assay Report Card

Basic Information

ID: ALA3858212

Type: Binding

Description: Induction of P-gp-mediated lysosomal membrane permeabilization in human KBV1 cells over expressing P-gp assessed as increase in LAMP2 fluorescence at 25 uM after 24 hrs in presence of P-gp inhibitor elacridar by TexasRed staining based immunofluorescence microscopic analysis

Organism: Homo sapiens

Cell type: KBV1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
284.392.272.27
353.503.373.37