Assay Report Card

Basic Information

ID: ALA3858219

Type: Functional

Description: Induction of oxidative stress-dependent lysosomal membrane permeabilization in human KBV1 cells over expressing P-gp assessed as decrease in cathepsin D and LAMP2 lysosomal colocalization at 10 uM after 24 hrs in presence of antioxidant N-acetyl-L-cysteine by TexasRed staining based immunofluorescence microscopic analysis

Organism: Homo sapiens

Cell type: KB-V1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
285.381.671.67
222.321.241.24