Basic Information
ID: ALA3858377
Type: Binding
Description: Antagonist activity at recombinant mouse P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of Bz-ATP-induced Ca2+ flux preincubated for 30 mins followed by agonist addition measured after 180 sec by calcium-4 dye based FLIPR assay
Organism: Mus musculus
Cell type: 1321-N1
Activity Charts
Bioactivity
Activity Types for Assay ALA3858377
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.81 | 4.84 | 4.84 |
| 439.80 | 4.23 | 4.23 |
| 437.82 | 5.44 | 5.44 |
| 420.82 | 4.70 | 4.70 |