Basic Information
ID: ALA3858388
Type: Binding
Description: Antagonist activity at P2X7 receptor in LPS-stimulated mouse whole blood assessed as inhibition of Bz-ATP-induced IL-1beta release incubated for 30 mins after LPS stimulation for 1 hr followed by agonist addition measured after 1.5 hrs by ELISA
Organism: Mus musculus
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA3858388
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.81 | 4.84 | 4.84 |