Basic Information
ID: ALA3858505
Type: Binding
Description: Inhibition of mPGES-1 in human whole blood assessed as reduction in LPS-induced PGE2 production preincubated for 30 mins followed by LPS stimulation for 20 to 24 hrs by LC/MS/MS analysis
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA3858505
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.38 | 3.51 | 3.51 |
| 381.52 | 3.69 | 3.69 |
| 429.99 | 4.41 | 4.41 |
| 367.49 | 3.30 | 3.30 |
| 411.55 | 3.05 | 3.05 |
| 409.57 | 4.06 | 4.06 |
| 412.50 | 4.23 | 4.23 |
| 367.54 | 4.56 | 4.56 |
| 409.57 | 4.06 | 4.06 |