Basic Information
ID: ALA3858507
Type: ADME
Description: Inhibition of COX-2 in human A549 cells assessed as reduction in recombinant human interleukin-1 beta-induced PGI2 production up to 10 uM preincubated for 30 mins measured after 18 hrs by ELISA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: A549
Target: Cyclooxygenase-2(ALA230)
Document: ALA3856235
Inhibition of COX-2 in human A549 cells assessed as reduction in recombinant human interleukin-1 beta-induced PGI2 production up to 10 uM preincubated for 30 mins measured after 18 hrs by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3858507
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.52 | 3.69 | 3.69 |
| 412.50 | 4.23 | 4.23 |
| 429.99 | 4.41 | 4.41 |
| 367.49 | 3.30 | 3.30 |
| 411.55 | 3.05 | 3.05 |
| 409.57 | 4.06 | 4.06 |
| 412.50 | 4.23 | 4.23 |
| 367.54 | 4.56 | 4.56 |
| 429.99 | 4.41 | 4.41 |
| 409.57 | 4.06 | 4.06 |