Inhibition of CYP2D6 in human hepatic microsomes assessed as reduction in probe substrate metabolism at 10 uM

Basic Information

ID: ALA3858515

Type: ADME

Description: Inhibition of CYP2D6 in human hepatic microsomes assessed as reduction in probe substrate metabolism at 10 uM

Format: BAO_0000019

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Target:  Cytochrome P450 2D6(ALA289)

Document:  ALA3856235

Inhibition of CYP2D6 in human hepatic microsomes assessed as reduction in probe substrate metabolism at 10 uM: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
411.553.053.05
409.574.064.06
409.574.064.06