Basic Information
ID: ALA3858697
Type: Binding
Description: Antagonist activity at recombinant human C-terminal His-tagged CBX7 chromodomain (8 to 62 residues) expressed in Escherichia coli Rosetta BL21(DE3)pLysS using biotin-labeled H3K9me3 measured after 30 mins by AlphaScreen assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3858697
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 809.06 | 3.40 | 3.40 |
| 809.06 | 3.40 | 3.40 |
| 580.79 | 3.06 | 3.06 |
| 823.09 | 3.64 | 3.64 |
| 822.02 | 1.41 | 1.41 |
| 807.99 | 1.02 | 1.02 |
| 849.04 | 0.17 | 0.17 |
| 924.19 | 4.03 | 4.03 |
| 739.87 | -0.56 | -0.56 |
| 752.95 | 2.02 | 2.02 |
| 808.98 | -0.61 | -0.61 |
| 876.07 | 1.52 | 1.52 |
| 752.95 | 2.02 | 2.02 |
| 834.03 | 1.26 | 1.26 |
| 781.01 | 2.92 | 2.92 |
| 781.01 | 2.83 | 2.83 |
| 738.93 | 1.71 | 1.71 |
| 768.95 | 1.72 | 1.72 |
| 795.04 | 3.01 | 3.01 |
| 490.67 | 1.44 | 1.44 |
| 808.08 | 2.92 | 2.92 |
| 796.96 | 1.50 | 1.50 |
| 752.95 | 2.02 | 2.02 |
| 793.96 | 0.58 | 0.58 |
| 839.03 | -0.74 | -0.74 |
| 791.99 | 2.12 | 2.12 |
| 796.99 | 0.53 | 0.53 |
| 766.98 | 2.27 | 2.27 |
| 767.93 | 0.05 | 0.05 |
| 848.05 | 1.89 | 1.89 |
| 782.02 | 2.37 | 2.37 |
| 796.99 | 0.53 | 0.53 |
| 578.73 | 0.35 | 0.35 |
| 807.99 | 0.97 | 0.97 |
| 737.00 | 3.47 | 3.47 |
| 782.96 | 0.19 | 0.19 |
| 809.06 | 2.94 | 2.94 |
| 823.09 | 3.79 | 3.79 |
| 806.92 | 2.73 | 2.73 |
| 795.98 | 0.83 | 0.83 |
| 781.95 | 0.48 | 0.48 |
| 803.01 | 2.79 | 2.79 |
| 725.91 | 1.07 | 1.07 |
| 874.09 | 1.90 | 1.90 |
| 822.02 | 1.36 | 1.36 |
| 796.99 | 0.53 | 0.53 |
| 824.08 | 2.47 | 2.47 |