ID: ALA3858844
Type: Binding
Description: Positive allosteric modulation of human mGlu2 receptor expressed in CHO cell membranes assessed as potentiation of glutamate-induced effect incubated for 30 mins prior to [35S]GTPgamma addition measured after 30 mins by scintillation counting method
Organism: Homo sapiens
Cell type: CHO
Bioactivity
Activity Types for Assay ALA3858844
EC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
400.45 | 5.08 | 5.08 |
344.89 | 4.69 | 4.69 |
464.48 | 5.79 | 5.79 |
428.50 | 5.25 | 5.25 |
450.46 | 5.36 | 5.36 |
432.47 | 5.22 | 5.22 |
432.47 | 5.16 | 5.16 |
451.44 | 4.30 | 4.30 |
444.50 | 4.84 | 4.84 |
480.48 | 5.16 | 5.16 |
414.48 | 5.08 | 5.08 |
487.48 | 3.50 | 3.50 |
450.46 | 5.36 | 5.36 |
464.48 | 5.79 | 5.79 |
448.92 | 5.73 | 5.73 |
414.48 | 5.08 | 5.08 |
482.47 | 5.80 | 5.80 |
484.35 | 5.33 | 5.33 |
466.45 | 5.02 | 5.02 |
451.44 | 4.30 | 4.30 |
465.47 | 4.69 | 4.69 |