Basic Information
ID: ALA3858845
Type: Binding
Description: Positive allosteric modulation of human mGlu2 receptor expressed in CHO cell membranes assessed as potentiation of glutamate-induced effect incubated for 30 mins prior to [35S]GTPgamma addition measured after 30 mins by scintillation counting method relative to control
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA3858845
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 400.45 | 5.08 | 5.08 |
| 344.89 | 4.69 | 4.69 |
| 464.48 | 5.79 | 5.79 |
| 428.50 | 5.25 | 5.25 |
| 450.46 | 5.36 | 5.36 |
| 432.47 | 5.22 | 5.22 |
| 432.47 | 5.16 | 5.16 |
| 451.44 | 4.30 | 4.30 |
| 444.50 | 4.84 | 4.84 |
| 480.48 | 5.16 | 5.16 |
| 414.48 | 5.08 | 5.08 |
| 487.48 | 3.50 | 3.50 |
| 450.46 | 5.36 | 5.36 |
| 464.48 | 5.79 | 5.79 |
| 448.92 | 5.73 | 5.73 |
| 414.48 | 5.08 | 5.08 |
| 482.47 | 5.80 | 5.80 |
| 484.35 | 5.33 | 5.33 |
| 466.45 | 5.02 | 5.02 |
| 451.44 | 4.30 | 4.30 |
| 465.47 | 4.69 | 4.69 |