Assay Report Card

Basic Information

ID: ALA3858856

Type: Binding

Description: Positive allosteric modulation at human mGlu2 receptor W773A mutant expressed in CHO-K1 cells assessed as potentiation of glutamate-induced effect incubated for 30 mins prior to [35S]GTPgamma addition measured after 30 mins by scintillation counting method

Organism: Homo sapiens

Cell type: CHO-K1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
400.455.085.08
344.894.694.69
451.444.304.30