Assay Report Card

Basic Information

ID: ALA3858901

Type: Functional

Description: Positive allosteric modulation of mGlu2 receptor in po dosed Sprague-Dawley rat sleep-wake EEG paradigm model assessed as plasma concentration required to show effect on sleep-wake cycle by electroencephalogram analysis

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Tissue: Plasma

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
400.455.085.08
344.894.694.69
451.444.304.30