Basic Information
ID: ALA3859178
Type: Binding
Description: Antagonist activity at P2X7 receptor in human whole blood assessed as reduction in LPS/BzATP-induced IL-1beta release preincubated with LPS-stimulated cells for 30 mins followed by BzATP addition measured after 1.5 hrs by ELISA
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA3859178
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 584.98 | 4.74 | 4.74 |
| 554.95 | 5.47 | 5.47 |
| 584.98 | 4.47 | 4.47 |