Basic Information
ID: ALA3859766
Type: Binding
Description: Inhibition of Escherichia coli GroEL/GroES expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured MDH refolding preincubated for 10 mins followed by ATP addition measured after 20 to 40 mins by fluorescence based assay
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA3859766
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 340.43 | 2.88 | 2.88 |
| 287.30 | 0.64 | 0.64 |
| 182.17 | -0.23 | -0.23 |
| 1297.30 | ||
| 532.65 | 5.45 | 5.45 |
| 533.63 | 5.71 | 5.71 |
| 381.44 | 2.24 | 2.24 |
| 541.56 | 5.37 | 5.37 |
| 641.57 | 7.13 | 7.13 |
| 505.58 | 5.10 | 5.10 |
| 574.47 | 6.40 | 6.40 |
| 555.60 | 4.84 | 4.84 |
| 593.60 | 4.49 | 4.49 |
| 641.57 | 7.13 | 7.13 |
| 537.58 | 4.51 | 4.51 |
| 621.71 | 5.11 | 5.11 |
| 541.56 | 5.37 | 5.37 |
| 555.60 | 4.84 | 4.84 |
| 533.63 | 5.38 | 5.38 |
| 565.63 | 5.11 | 5.11 |
| 541.56 | 5.37 | 5.37 |
| 593.60 | 4.49 | 4.49 |
| 641.64 | 5.31 | 5.31 |
| 595.57 | 4.91 | 4.91 |
| 621.65 | 4.67 | 4.67 |
| 555.60 | 4.84 | 4.84 |
| 605.70 | 7.40 | 7.40 |
| 437.54 | 3.80 | 3.80 |
| 537.58 | 4.51 | 4.51 |
| 663.37 | 6.62 | 6.62 |
| 535.61 | 4.26 | 4.26 |
| 589.57 | 4.17 | 4.17 |
| 565.63 | 5.11 | 5.11 |
| 533.63 | 5.71 | 5.71 |
| 619.73 | 6.32 | 6.32 |
| 621.65 | 4.67 | 4.67 |
| 604.71 | 7.14 | 7.14 |
| 489.38 | 4.02 | 4.02 |
| 535.61 | 4.26 | 4.26 |
| 595.57 | 4.91 | 4.91 |
| 621.65 | 4.67 | 4.67 |
| 535.61 | 4.26 | 4.26 |
| 595.57 | 4.91 | 4.91 |
| 641.57 | 7.13 | 7.13 |
| 517.64 | 5.22 | 5.22 |
| 574.47 | 6.40 | 6.40 |
| 593.60 | 4.49 | 4.49 |
| 565.63 | 5.11 | 5.11 |
| 663.37 | 6.62 | 6.62 |
| 621.71 | 5.11 | 5.11 |
| 663.37 | 6.62 | 6.62 |
| 574.47 | 6.40 | 6.40 |
| 537.58 | 4.51 | 4.51 |